Read Our Publications

Findings from the lab—dive into the learnings that took place at the LGR

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Functional genomics in stem cell models: considerations and applications
Kaivalya Shevade, Sailaja Peddada, Karl Mader, and Laralynne Przybyla published in frontiers in Cell and Developmental Biology
Compact CRISPR genetic screens enabled by improved guide RNA library cloning
Seok-Jin Heo, Lauren D. Enriquez, Scot Federman, Amy Y. Chang, Rachel Mace, Kaivalya Shevade, Phuong Nguyen, Adam J. Litterman, Shawn Shafer, Laralynne Przybyla, Eric D. Chow
A New Era in Functional Genomics Screens
Przybyla L and Gilbert L. Nature Reviews Genetics.

Covid Publications & Citations

Given the urgent challenge of the COVID-19 pandemic, the research award was focused on programs which were spearheading COVID-19 research through wet-lab and computational approaches with a focus on, but not limited to, CRISPR-driven approaches.
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
Bracken C, Lim S, Solomon P, Rettko N, Nguyen D, Zha B, Schaefer K, Byrnes J, Zhou J, Lui I, Liu J, Pance K, QCRG Structural Biology Consortium, Zhou X, Leung K, Wells J. Nature Chemical Biology
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
Deng X, Garcia-Knight M, Khalid M, Ott M, Andino R, Chiu C et al. Cell.
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Bouhaddou M, Memon D, Meyer B, Swaney D, Beltrao P, Krogan N et al. Cell.
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
Gordon D, Hiatt J, Bouhaddou M, Rezelj V, Ulferts S, Braberg H, Jureka A, Obernier K,Guo J, Krogan N et al. Science.

Check out our past and present projects.